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Academic Journal

Variation in the gene Tas1r3 reveals complex temporal properties of mouse brainstem taste responses to sweeteners.

  • Authors : McCaughey SA; Center for Medical Education, Ball State University, Muncie, Indiana.; Monell Chemical Senses Center, Philadelphia, Pennsylvania.

Subjects: Taste* ; Taste Perception*; Action Potentials/Action Potentials/Action Potentials/*drug effects

  • Source: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2021 Nov 01; Vol. 321 (5), pp. R751-R767. Date of ElectronicPublisher: American Physiological Society Country of Publication: United States NLM ID: 100901230 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Structural Insights into the Unique Modes of Relaxin-Binding and Tethered-Agonist Mediated Activation of RXFP1 and RXFP2.

  • Authors : Sethi A; Department of Biochemistry & Pharmacology, The University of Melbourne, Parkville, Victoria 3052, Australia; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3052, Australia.

Subjects: Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/*chemistry ; Receptors, Peptide/Receptors, Peptide/Receptors, Peptide/*chemistry ; Relaxin/Relaxin/Relaxin/*chemistry

  • Source: Journal of molecular biology [J Mol Biol] 2021 Oct 15; Vol. 433 (21), pp. 167217. Date of Electronic Publication: 2021 Aug 26.Publisher: Elsevier Country of Publication: England NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638

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Academic Journal

The GPR171 pathway suppresses T cell activation and limits antitumor immunity.

  • Authors : Fujiwara Y; Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Torphy RJ

Subjects: Immunity*; Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/*chemistry ; Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/*genetics

  • Source: Nature communications [Nat Commun] 2021 Oct 06; Vol. 12 (1), pp. 5857. Date of Electronic Publication: 2021 Oct 06.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

G protein-coupled receptor 39 activation alleviates oxidized low-density lipoprotein-induced macrophage inflammatory response, lipid accumulation and apoptosis by inducing A20 expression.

  • Authors : Chen L; Department of Vascular Surgery, Provincial Hospital Affiliated to Anhui Medical University, Hefei City, Anhui Province, China.; Fang Z

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects; Inflammation/Inflammation/Inflammation/*pathology ; Lipids/Lipids/Lipids/*chemistry

  • Source: Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 4070-4080.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101581063 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Pharmacophore-guided repurposing of fibrates and retinoids as GPR40 allosteric ligands with activity on insulin release.

  • Authors : Cione E; Department of Pharmacy, Health and Nutritional Sciences (Department of Excellence 2018-2022), University of Calabria, Rende, Italy.; Caroleo MC

Subjects: Drug Repositioning*; Fibric Acids/Fibric Acids/Fibric Acids/*pharmacology ; Insulin/Insulin/Insulin/*metabolism

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 377-383.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

The selective TAAR1 partial agonist RO5263397 promoted novelty recognition memory in mice.

  • Authors : Wu R; Department of Pharmacology and Toxicology, University At Buffalo, The State University of New York, 955 Main Street, Buffalo, NY, 14214, USA.; Medical College of Yangzhou University, Yangzhou, China.

Subjects: Oxazoles* ; Receptors, G-Protein-Coupled*; Animals

  • Source: Psychopharmacology [Psychopharmacology (Berl)] 2021 Nov; Vol. 238 (11), pp. 3221-3228. Date of Electronic Publication: 2021 Jul 22.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Accurate Binding Configuration Prediction of a G-Protein-Coupled Receptor to Its Antagonist Using Multicanonical Molecular Dynamics-Based Dynamic Docking.

  • Authors : Bekker GJ; Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.; Araki M

Subjects: Molecular Dynamics Simulation* ; Receptors, G-Protein-Coupled*/Receptors, G-Protein-Coupled*/Receptors, G-Protein-Coupled*/metabolism; Binding Sites

  • Source: Journal of chemical information and modeling [J Chem Inf Model] 2021 Oct 25; Vol. 61 (10), pp. 5161-5171. Date of Electronic Publication: 2021 Sep 22.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Receptor-Loaded Virion Endangers GPCR Signaling: Mechanistic Exploration of SARS-CoV-2 Infections and Pharmacological Implications.

  • Authors : Zhang Q; Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.; Friedman PA

Subjects: COVID-19/COVID-19/COVID-19/*pathology ; Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/*metabolism; Antiviral Agents/Antiviral Agents/Antiviral Agents/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Oct 11; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

G protein-coupled estrogen receptor regulates the KLF2-dependent eNOS expression by activating of Ca 2+ and EGFR signaling pathway in human endothelial cells.

  • Authors : Park JS; College of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea.; Lee GH

Subjects: Calcium Signaling/Calcium Signaling/Calcium Signaling/*physiology ; Human Umbilical Vein Endothelial Cells/Human Umbilical Vein Endothelial Cells/Human Umbilical Vein Endothelial Cells/*metabolism ; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*metabolism

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2021 Oct; Vol. 192, pp. 114721. Date of Electronic Publication: 2021 Aug 04.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

GPCR-ErbB transactivation pathways and clinical implications.

  • Authors : Palanisamy S; Department of Medicine, Stanford University, Palo Alto, CA, USA. Electronic address: .; Xue C

Subjects: Cardiovascular Diseases/Cardiovascular Diseases/Cardiovascular Diseases/*pathology ; ErbB Receptors/ErbB Receptors/ErbB Receptors/*metabolism ; Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/*metabolism

  • Source: Cellular signalling [Cell Signal] 2021 Oct; Vol. 86, pp. 110092. Date of Electronic Publication: 2021 Jul 22.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  34,326 نتائج ""Receptors, G-Protein-Coupled""