CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT.

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  • معلومة اضافية
    • Publication Information:
      Public Library of Science (PLoS), 2015.
    • Publication Date:
      2015
    • Collection:
      LCC:Medicine
      LCC:Science
    • Abstract:
      To determine inter-session and intra/inter-individual variations of the attenuations of aortic blood/myocardium with MDCT in the context of calcium scoring. To evaluate whether these variations are dependent on patients' characteristics.Fifty-four volunteers were evaluated with calcium scoring non-enhanced CT. We measured attenuations (inter-individual variation) and standard deviations (SD, intra-individual variation) of the blood in the ascending aorta and of the myocardium of left ventricle. Every volunteer was examined twice to study the inter-session variation. The fat pad thickness at the sternum and noise (SD of air) were measured too. These values were correlated with the measured aortic/ventricular attenuations and their SDs (Pearson). Historically fixed thresholds (90 and 130 HU) were tested against different models based on attenuations of blood/ventricle.The mean attenuation was 46 HU (range, 17-84 HU) with mean SD 23 HU for the blood, and 39 HU (10-82 HU) with mean SD 18 HU for the myocardium. The attenuation/SD of the blood were significantly higher than those of the myocardium (p < 0.01). The inter-session variation was not significant. There was a poor correlation between SD of aortic blood/ventricle with fat thickness/noise. Based on existing models, 90 HU threshold offers a confidence interval of approximately 95% and 130 HU more than 99%.Historical thresholds offer high confidence intervals for exclusion of aortic blood/myocardium and by the way for detecting calcifications. Nevertheless, considering the large variations of blood/myocardium CT values and the influence of patient's characteristics, a better approach might be an adaptive threshold.
    • File Description:
      electronic resource
    • ISSN:
      1932-6203
    • Relation:
      http://europepmc.org/articles/PMC4397043?pdf=render; https://doaj.org/toc/1932-6203
    • Accession Number:
      10.1371/journal.pone.0124175
    • Rights:
      Journal Licence: CC BY
    • Accession Number:
      edsdoj.8a5e9ddb3bae441d9c07fbbde5c8cfdd
  • Citations
    • ABNT:
      SALAH D QANADLI et al. CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT. PLoS ONE, [s. l.], n. 4, p. e0124175, 2015. Disponível em: . Acesso em: 15 nov. 2019.
    • AMA:
      Salah D Qanadli, Anne-Marie Jouannic, Jamshid Dehmeshki, Tri-Linh Lu. CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT. PLoS ONE. 2015;(4):e0124175. doi:10.1371/journal.pone.0124175.
    • APA:
      Salah D Qanadli, Anne-Marie Jouannic, Jamshid Dehmeshki, & Tri-Linh Lu. (2015). CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT. PLoS ONE, (4), e0124175. https://doi.org/10.1371/journal.pone.0124175
    • Chicago/Turabian: Author-Date:
      Salah D Qanadli, Anne-Marie Jouannic, Jamshid Dehmeshki, and Tri-Linh Lu. 2015. “CT Attenuation Values of Blood and Myocardium: Rationale for Accurate Coronary Artery Calcifications Detection with Multi-Detector CT.” PLoS ONE, no. 4: e0124175. doi:10.1371/journal.pone.0124175.
    • Harvard:
      Salah D Qanadli et al. (2015) ‘CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT’, PLoS ONE, (4), p. e0124175. doi: 10.1371/journal.pone.0124175.
    • Harvard: Australian:
      Salah D Qanadli, Anne-Marie Jouannic, Jamshid Dehmeshki & Tri-Linh Lu 2015, ‘CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT’, PLoS ONE, no. 4, p. e0124175, viewed 15 November 2019, .
    • MLA:
      Salah D Qanadli, et al. “CT Attenuation Values of Blood and Myocardium: Rationale for Accurate Coronary Artery Calcifications Detection with Multi-Detector CT.” PLoS ONE, no. 4, 2015, p. e0124175. EBSCOhost, doi:10.1371/journal.pone.0124175.
    • Chicago/Turabian: Humanities:
      Salah D Qanadli, Anne-Marie Jouannic, Jamshid Dehmeshki, and Tri-Linh Lu. “CT Attenuation Values of Blood and Myocardium: Rationale for Accurate Coronary Artery Calcifications Detection with Multi-Detector CT.” PLoS ONE, no. 4 (2015): e0124175. doi:10.1371/journal.pone.0124175.
    • Vancouver/ICMJE:
      Salah D Qanadli, Anne-Marie Jouannic, Jamshid Dehmeshki, Tri-Linh Lu. CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT. PLoS ONE [Internet]. 2015 [cited 2019 Nov 15];(4):e0124175. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsdoj&AN=edsdoj.8a5e9ddb3bae441d9c07fbbde5c8cfdd&custid=s8280428