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Multicentre randomised trial comparing contact force with electrical coupling index in atrial flutter ablation (VERISMART trial).

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  • معلومة اضافية
    • Publication Information:
      Public Library of Science (PLoS), 2019.
    • Publication Date:
      2019
    • Collection:
      LCC:Medicine
      LCC:Science
    • Abstract:
      INTRODUCTION:Electrical coupling index (ECI) and contact force (CF) have been developed to aid lesion formation during catheter ablation. ECI measures tissue impedance and capacitance whilst CF measures direct contact. The aim was to determine whether the presence of catheter / tissue interaction information, such as ECI and CF, reduce time to achieve bidirectional cavotricuspid isthmus block during atrial flutter (AFL) ablation. METHODS:Patients with paroxysmal or persistent AFL were randomised to CF visible (range 5-40g), CF not visible, ECI visible (change of 12%) or ECI not visible. Follow-up occurred at 3 and 6 months and included a 7 day ECG recording. The primary endpoint was time to bidirectional cavotricuspid isthmus block. RESULTS:114 patients were randomised, 16 were excluded. Time to bidirectional block was significantly shorter when ECI was visible (median 30.0 mins (IQR 31) to median 10.5mins (IQR 12) p 0.023) versus ECI not visible. There was a trend towards a shorter time to bidirectional block when CF was visible. Higher force was applied when CF was visible (median 9.03g (IQR 7.4) vs. 11.3g (5.5) p 0.017). There was no difference in the acute recurrence of conduction between groups. The complication rate was 2%, AFL recurrence was 1.1% and at 6 month follow-up, 12% had atrial fibrillation. CONCLUSION:The use of tissue contact information during AFL ablation was associated with reduced time taken to achieve bidirectional block when ECI was visible. Contact force data improved contact when visible with a trend towards a reduction in the procedural endpoint. ClinicalTrials.gov trial identifier: NCT02490033.
    • File Description:
      electronic resource
    • ISSN:
      1932-6203
    • Relation:
      https://doaj.org/toc/1932-6203
    • Accession Number:
      10.1371/journal.pone.0212903
    • Rights:
      Journal Licence: CC BY
    • Accession Number:
      edsdoj.85125532b8e470cbb6bdc2f0b7abb42
  • Citations
    • ABNT:
      GORDON A BEGG et al. Multicentre randomised trial comparing contact force with electrical coupling index in atrial flutter ablation (VERISMART trial). PLoS ONE, [s. l.], v. 14, n. 4, p. e0212903, 2019. DOI 10.1371/journal.pone.0212903. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsdoj&AN=edsdoj.85125532b8e470cbb6bdc2f0b7abb42&custid=s8280428. Acesso em: 14 jul. 2020.
    • AMA:
      Gordon A Begg, James O’Neill, Afzal Sohaib, et al. Multicentre randomised trial comparing contact force with electrical coupling index in atrial flutter ablation (VERISMART trial). PLoS ONE. 2019;14(4):e0212903. doi:10.1371/journal.pone.0212903.
    • AMA11:
      Gordon A Begg, James O’Neill, Afzal Sohaib, et al. Multicentre randomised trial comparing contact force with electrical coupling index in atrial flutter ablation (VERISMART trial). PLoS ONE. 2019;14(4):e0212903. doi:10.1371/journal.pone.0212903
    • APA:
      Gordon A Begg, James O’Neill, Afzal Sohaib, Ailsa McLean, Chris B Pepper, Lee N Graham, Andrew J Hogarth, Stephen P Page, Richard G Gillott, Nicola Hill, Jacqueline Walshaw, Richard J Schilling, Prapa Kanagaratnam, & Muzahir H Tayebjee. (2019). Multicentre randomised trial comparing contact force with electrical coupling index in atrial flutter ablation (VERISMART trial). PLoS ONE, 14(4), e0212903. https://doi.org/10.1371/journal.pone.0212903
    • Chicago/Turabian: Author-Date:
      Gordon A Begg, James O’Neill, Afzal Sohaib, Ailsa McLean, Chris B Pepper, Lee N Graham, Andrew J Hogarth, et al. 2019. “Multicentre Randomised Trial Comparing Contact Force with Electrical Coupling Index in Atrial Flutter Ablation (VERISMART Trial).” PLoS ONE 14 (4): e0212903. doi:10.1371/journal.pone.0212903.
    • Harvard:
      Gordon A Begg et al. (2019) ‘Multicentre randomised trial comparing contact force with electrical coupling index in atrial flutter ablation (VERISMART trial)’, PLoS ONE, 14(4), p. e0212903. doi: 10.1371/journal.pone.0212903.
    • Harvard: Australian:
      Gordon A Begg, James O’Neill, Afzal Sohaib, Ailsa McLean, Chris B Pepper, Lee N Graham, Andrew J Hogarth, Stephen P Page, Richard G Gillott, Nicola Hill, Jacqueline Walshaw, Richard J Schilling, Prapa Kanagaratnam & Muzahir H Tayebjee 2019, ‘Multicentre randomised trial comparing contact force with electrical coupling index in atrial flutter ablation (VERISMART trial)’, PLoS ONE, vol. 14, no. 4, p. e0212903, viewed 14 July 2020, .
    • MLA:
      Gordon A Begg, et al. “Multicentre Randomised Trial Comparing Contact Force with Electrical Coupling Index in Atrial Flutter Ablation (VERISMART Trial).” PLoS ONE, vol. 14, no. 4, Jan. 2019, p. e0212903. EBSCOhost, doi:10.1371/journal.pone.0212903.
    • Chicago/Turabian: Humanities:
      Gordon A Begg, James O’Neill, Afzal Sohaib, Ailsa McLean, Chris B Pepper, Lee N Graham, Andrew J Hogarth, et al. “Multicentre Randomised Trial Comparing Contact Force with Electrical Coupling Index in Atrial Flutter Ablation (VERISMART Trial).” PLoS ONE 14, no. 4 (January 1, 2019): e0212903. doi:10.1371/journal.pone.0212903.
    • Vancouver/ICMJE:
      Gordon A Begg, James O’Neill, Afzal Sohaib, Ailsa McLean, Chris B Pepper, Lee N Graham, et al. Multicentre randomised trial comparing contact force with electrical coupling index in atrial flutter ablation (VERISMART trial). PLoS ONE [Internet]. 2019 Jan 1 [cited 2020 Jul 14];14(4):e0212903. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsdoj&AN=edsdoj.85125532b8e470cbb6bdc2f0b7abb42&custid=s8280428