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Effectiveness of adding ketamine to ropivacaine infusion via femoral nerve catheter after knee anterior cruciate ligament repair.

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  • معلومة اضافية
    • Subject Terms:
    • Author-Supplied Keywords:
      ketamine
      pain
      ropivacaine
      visual analogue scale
    • NAICS/Industry Codes:
      325410 Pharmaceutical and medicine manufacturing
      325411 Medicinal and Botanical Manufacturing
    • Abstract:
      Background: Elective knee surgery for repairing anterior cruciate ligament is usually associated with moderate to severe postoperative pain, and, therefore, selecting appropriate analgesia can considerably facilitate pain control and patient’s discharge. This study was designed to compare the analgesic effectiveness of administration of ropivacaine or ropivacaine plus ketamine on pain control and improvement of muscle weakness after anterior cruciate ligament repair in adults. Materials and Methods: A double-blind randomized study which performed in Operating room and Sixty six patients with American Society of Anesthesiologists health status I to II that underwent elective knee surgery for repairing anterior cruciate ligament under spinal anesthesia were enrolled. Patients were randomly allocated to receive either ropivacaine 0.2% or an equivalent volume of ropivacaine 0.1% plus 1.0 mg/kg ketamine via continuous femoral block with pump infusion. The patients were familiarized with a 10-point verbal analog scale. Quadriceps muscle weakness and sedation score were assessed based on relevant scales. Parameters assessment were obtained from all patients immediately after PACU entrance, and postoperative assessment was performed at 4, 8, 12, 16, 20, 24, 30, 36, 42, and 48 h after the operation. Results: The data of 31 patients who received ropivacaine and of 33 patients in ketamine-ropivacaine group were eligible for analysis. Visual analogue scale (VAS) scores differed at various time points after surgery, with higher scores in patients who received concomitant ketamine and ropivacaine (P < 0.05). The degree of quadriceps muscle weakness was similar between the groups at the different time points. Patients in ropivacaine group rated better quality of pain control with appropriate sedation in comparison with the patients in ketamine/ropivacaine group. Conclusion: Our study shows that the addition of a ketamine 1 mg/kg to 0.1% ropivacaine via pump infusion after repairing anterior cruciate ligament could not improve pain control and muscle weakness. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of Journal of Research in Medical Sciences is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
    • Author Affiliations:
      1Department of Anesthesiology, Hazrat Rasul Medical Complex
      2Resident of Anesthesiology, Tehran University of Medical Sciences, Tehran, Iran
    • ISSN:
      1735-1995
    • Accession Number:
      92889038
  • Citations
    • ABNT:
      RAHIMZADEH, P. et al. Effectiveness of adding ketamine to ropivacaine infusion via femoral nerve catheter after knee anterior cruciate ligament repair. Journal of Research in Medical Sciences, [s. l.], v. 18, n. 8, p. 632–636, 2013. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=92889038&custid=s8280428. Acesso em: 30 maio. 2020.
    • AMA:
      Rahimzadeh P, Reza Faiz SH, Ziyaeifard M, Niknam K. Effectiveness of adding ketamine to ropivacaine infusion via femoral nerve catheter after knee anterior cruciate ligament repair. Journal of Research in Medical Sciences. 2013;18(8):632-636. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=92889038&custid=s8280428. Accessed May 30, 2020.
    • APA:
      Rahimzadeh, P., Reza Faiz, S. H., Ziyaeifard, M., & Niknam, K. (2013). Effectiveness of adding ketamine to ropivacaine infusion via femoral nerve catheter after knee anterior cruciate ligament repair. Journal of Research in Medical Sciences, 18(8), 632–636.
    • Chicago/Turabian: Author-Date:
      Rahimzadeh, Poupak, Seyed Hamid Reza Faiz, Mohsen Ziyaeifard, and Keyvan Niknam. 2013. “Effectiveness of Adding Ketamine to Ropivacaine Infusion via Femoral Nerve Catheter after Knee Anterior Cruciate Ligament Repair.” Journal of Research in Medical Sciences 18 (8): 632–36. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=92889038&custid=s8280428.
    • Harvard:
      Rahimzadeh, P. et al. (2013) ‘Effectiveness of adding ketamine to ropivacaine infusion via femoral nerve catheter after knee anterior cruciate ligament repair’, Journal of Research in Medical Sciences, 18(8), pp. 632–636. Available at: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=92889038&custid=s8280428 (Accessed: 30 May 2020).
    • Harvard: Australian:
      Rahimzadeh, P, Reza Faiz, SH, Ziyaeifard, M & Niknam, K 2013, ‘Effectiveness of adding ketamine to ropivacaine infusion via femoral nerve catheter after knee anterior cruciate ligament repair’, Journal of Research in Medical Sciences, vol. 18, no. 8, pp. 632–636, viewed 30 May 2020, .
    • MLA:
      Rahimzadeh, Poupak, et al. “Effectiveness of Adding Ketamine to Ropivacaine Infusion via Femoral Nerve Catheter after Knee Anterior Cruciate Ligament Repair.” Journal of Research in Medical Sciences, vol. 18, no. 8, Aug. 2013, pp. 632–636. EBSCOhost, search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=92889038&custid=s8280428.
    • Chicago/Turabian: Humanities:
      Rahimzadeh, Poupak, Seyed Hamid Reza Faiz, Mohsen Ziyaeifard, and Keyvan Niknam. “Effectiveness of Adding Ketamine to Ropivacaine Infusion via Femoral Nerve Catheter after Knee Anterior Cruciate Ligament Repair.” Journal of Research in Medical Sciences 18, no. 8 (August 2013): 632–36. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=92889038&custid=s8280428.
    • Vancouver/ICMJE:
      Rahimzadeh P, Reza Faiz SH, Ziyaeifard M, Niknam K. Effectiveness of adding ketamine to ropivacaine infusion via femoral nerve catheter after knee anterior cruciate ligament repair. Journal of Research in Medical Sciences [Internet]. 2013 Aug [cited 2020 May 30];18(8):632–6. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=92889038&custid=s8280428