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Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010.

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  • معلومة اضافية
    • Abstract:
      We aimed to investigate the association of various obesity parameters and phenotypes with hypertension in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2008–2010, a total of 16,363 subjects (8,184 men and 8,179 women) were analyzed. Hypertension was defined as blood pressure of 140/90 mm Hg or higher or taking antihypertensive medication. Multiple logistic regression analysis was used to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Higher obesity parameters [body mass index (BMI) representing general obesity, waist circumference (WC) representing central obesity, and percentage body fat (PBF) representing elevated body fat] were consistently associated with increased odds of prevalent hypertension (OR, 7.54; 95% CI, 5.89–9.65 for BMI ≥30 vs. 18.5–23; OR, 3.97; 95% CI, 3.41–4.63 for WC ≥95 cm in males and ≥90 cm in females vs. <85 cm in males and <80 cm in females; OR, 3.56; 95% CI, 3.05–4.15 for PBF, highest vs. lowest quartile; all p trends<0.0001). These associations were stronger in the younger age group (<40 years), and were observed in both sexes. Furthermore, even in individuals with normal BMI (18.5–23), the odds of prevalent hypertension were consistently increased in those with central obesity (WC≥90 cm in males, WC≥80 cm in females; normal weight central obesity phenotype) (OR, 1.89; 95% CI, 1.63–2.19) and those with high PBF (highest quartile of PBF; normal weight obesity phenotype) (OR, 1.49; 95% CI, 1.25–1.77). These associations were consistent with updated hypertension guidelines in 2017. Obesity may be positively associated with hypertension, regardless of obesity parameters. Even within normal BMI range, high WC and high PBF may be associated with hypertension. [ABSTRACT FROM AUTHOR]
    • Abstract:
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    • Author Affiliations:
      1Division of Cardiology, Department of Medicine, Mayo Clinic, Scottsdale, AZ, United States of America
      2Division of Cardiology, Department of Medicine, University of California Riverside, Riverside, CA, United States of America
      3Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America
      4Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States of America
      5Department of Statistics and Actuarial Science, Soongsil University, Seoul, Korea
      6Department of Emergency Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
      7Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
      8Division of Endocrinology and Metabolism, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
    • ISSN:
      1932-6203
    • Accession Number:
      10.1371/journal.pone.0230616
    • Accession Number:
      142835816
  • Citations
    • ABNT:
      SEOK LEE, H. et al. Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010. PLoS ONE, [s. l.], v. 15, n. 4, p. 1–14, 2020. DOI 10.1371/journal.pone.0230616. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=142835816&custid=s8280428. Acesso em: 3 jul. 2020.
    • AMA:
      Seok Lee H, Park Y-M, Han K, et al. Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010. PLoS ONE. 2020;15(4):1-14. doi:10.1371/journal.pone.0230616.
    • AMA11:
      Seok Lee H, Park Y-M, Han K, et al. Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010. PLoS ONE. 2020;15(4):1-14. doi:10.1371/journal.pone.0230616
    • APA:
      Seok Lee, H., Park, Y.-M., Han, K., Yang, J.-H., Lee, S., Lee, S., Yoo, S., & Kim, S. R. (2020). Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010. PLoS ONE, 15(4), 1–14. https://doi.org/10.1371/journal.pone.0230616
    • Chicago/Turabian: Author-Date:
      Seok Lee, Hong, Yong-Moon Park, Kyungdo Han, Jin-Hong Yang, Seungwon Lee, Seong‐Su Lee, Soonjib Yoo, and Sung Rae Kim. 2020. “Obesity-Related Hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010.” PLoS ONE 15 (4): 1–14. doi:10.1371/journal.pone.0230616.
    • Harvard:
      Seok Lee, H. et al. (2020) ‘Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010’, PLoS ONE, 15(4), pp. 1–14. doi: 10.1371/journal.pone.0230616.
    • Harvard: Australian:
      Seok Lee, H, Park, Y-M, Han, K, Yang, J-H, Lee, Seungwon, Lee, Seong‐Su, Yoo, S & Kim, SR 2020, ‘Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010’, PLoS ONE, vol. 15, no. 4, pp. 1–14, viewed 3 July 2020, .
    • MLA:
      Seok Lee, Hong, et al. “Obesity-Related Hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010.” PLoS ONE, vol. 15, no. 4, Apr. 2020, pp. 1–14. EBSCOhost, doi:10.1371/journal.pone.0230616.
    • Chicago/Turabian: Humanities:
      Seok Lee, Hong, Yong-Moon Park, Kyungdo Han, Jin-Hong Yang, Seungwon Lee, Seong‐Su Lee, Soonjib Yoo, and Sung Rae Kim. “Obesity-Related Hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010.” PLoS ONE 15, no. 4 (April 21, 2020): 1–14. doi:10.1371/journal.pone.0230616.
    • Vancouver/ICMJE:
      Seok Lee H, Park Y-M, Han K, Yang J-H, Lee S, Lee S, et al. Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010. PLoS ONE [Internet]. 2020 Apr 21 [cited 2020 Jul 3];15(4):1–14. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=142835816&custid=s8280428