Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia.

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  • معلومة اضافية
    • Subject Terms:
    • Author-Supplied Keywords:
      Malaysia
      neglected tropical diseases
      Orang Asli
      schoolchildren
      soil-transmitted helminth
      Strongyloides stercoralis
    • Abstract:
      This cross-sectional study aimed to determine the prevalence and risk factors of S. stercoralis infection among 1142 Orang Asli primary schoolchildren in six different states of Peninsular Malaysia. Fecal samples were examined using direct smear, formalin-ether sedimentation (FES), agar plate culture (APC) and PCR techniques. Overall, 15.8% of the children were found to be infected with S. stercoralis. The prevalence was 0.2, 1.3, 15.2 and 13.7% by direct smear, FES, APC and PCR, respectively. Multivariate analysis showed that an age of >10 years, being male, belonging to a Proto-Malay tribe, belonging to the Senoi tribe, indiscriminate defecation, using an unimproved water source for drinking water and not wearing shoes when outside were the significant risk factors of infection among these children. In conclusion, we provide new evidence on the occurrence of S. stercoralis in Malaysia to show that there is a relatively high prevalence of infection among Orang Asli schoolchildren. Therefore, the use of specific methods for detecting S. stercoralis should be considered when screening these children for intestinal parasites. Moreover, prevention and control measures specific to S. stercoralis should be integrated into the intestinal parasitic infections control programme in Malaysia. [ABSTRACT FROM AUTHOR]
    • Abstract:
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    • Author Affiliations:
      1Medical Research Centre, Jazan University, 45142 Jazan, Kingdom of Saudi Arabia
      2Department of Parasitology, Faculty of Medicine and Health Sciences, Sana'a University, 1247 Sana'a, Yemen
      3Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
      4Department of Medical Laboratories, Faculty of Medical Sciences, Hodeidah University, Hodeidah, Yemen
      5Department of Microbiology and Parasitology, Faculty of Medicine and Health Sciences, University of Aden, Aden, Yemen
      6School of Health Technology, Club Road, Nassarawa, Kano, 700282 Kano State, Nigeria
      7Centre of Medical Laboratory Technology, Faculty of Health Sciences, Universiti Teknologi MARA, Puncak Alam Campus, 42300 Selangor, Malaysia
      8Integrative Pharmacogenomics Institute, Universiti Teknologi MARA, Puncak Alam Campus, 42300 Selangor, Malaysia
      9Institute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia
    • ISSN:
      0031-1820
    • Accession Number:
      10.1017/S0031182019000945
    • Accession Number:
      138526867
  • Citations
    • ABNT:
      AL-MEKHLAFI, H. M. et al. Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia. Parasitology, [s. l.], v. 146, n. 12, p. 1602–1614, 2019. Disponível em: . Acesso em: 18 nov. 2019.
    • AMA:
      Al-Mekhlafi HM, Nasr NA, Lim YAL, et al. Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia. Parasitology. 2019;146(12):1602-1614. doi:10.1017/S0031182019000945.
    • APA:
      Al-Mekhlafi, H. M., Nasr, N. A., Lim, Y. A. L., Elyana, F. N., Sady, H., Atroosh, W. M., … Mahmud, R. (2019). Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia. Parasitology, 146(12), 1602–1614. https://doi.org/10.1017/S0031182019000945
    • Chicago/Turabian: Author-Date:
      Al-Mekhlafi, Hesham M., Nabil A. Nasr, Yvonne A. L. Lim, Fatin Nur Elyana, Hany Sady, Wahib M. Atroosh, Salwa Dawaki, Tengku Shahrul Anuar, Rahmah Noordin, and Rohela Mahmud. 2019. “Prevalence and Risk Factors of Strongyloides Stercoralis Infection among Orang Asli Schoolchildren: New Insights into the Epidemiology, Transmission and Diagnosis of Strongyloidiasis in Malaysia.” Parasitology 146 (12): 1602–14. doi:10.1017/S0031182019000945.
    • Harvard:
      Al-Mekhlafi, H. M. et al. (2019) ‘Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia’, Parasitology, 146(12), pp. 1602–1614. doi: 10.1017/S0031182019000945.
    • Harvard: Australian:
      Al-Mekhlafi, HM, Nasr, NA, Lim, YAL, Elyana, FN, Sady, H, Atroosh, WM, Dawaki, S, Anuar, TS, Noordin, R & Mahmud, R 2019, ‘Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia’, Parasitology, vol. 146, no. 12, pp. 1602–1614, viewed 18 November 2019, .
    • MLA:
      Al-Mekhlafi, Hesham M., et al. “Prevalence and Risk Factors of Strongyloides Stercoralis Infection among Orang Asli Schoolchildren: New Insights into the Epidemiology, Transmission and Diagnosis of Strongyloidiasis in Malaysia.” Parasitology, vol. 146, no. 12, Oct. 2019, pp. 1602–1614. EBSCOhost, doi:10.1017/S0031182019000945.
    • Chicago/Turabian: Humanities:
      Al-Mekhlafi, Hesham M., Nabil A. Nasr, Yvonne A. L. Lim, Fatin Nur Elyana, Hany Sady, Wahib M. Atroosh, Salwa Dawaki, Tengku Shahrul Anuar, Rahmah Noordin, and Rohela Mahmud. “Prevalence and Risk Factors of Strongyloides Stercoralis Infection among Orang Asli Schoolchildren: New Insights into the Epidemiology, Transmission and Diagnosis of Strongyloidiasis in Malaysia.” Parasitology 146, no. 12 (October 2019): 1602–14. doi:10.1017/S0031182019000945.
    • Vancouver/ICMJE:
      Al-Mekhlafi HM, Nasr NA, Lim YAL, Elyana FN, Sady H, Atroosh WM, et al. Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia. Parasitology [Internet]. 2019 Oct [cited 2019 Nov 18];146(12):1602–14. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=138526867&custid=s8280428