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Regional differences in anterior cruciate ligament imaging biomarkers: T2 and T2* values.

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  • معلومة اضافية
    • Author-Supplied Keywords:
      knee
      MRI
      structural composition
    • NAICS/Industry Codes:
      621512 Diagnostic Imaging Centers
    • Abstract:
      Introduction: Imaging biomarkers such as T2 and T2* relaxation times have been used in a variety of tissues as surrogates of structural components. Before using such techniques to assess ACL tissue, healthy values must be established. The purpose of this study was to characterize T2 and T2* ACL relaxation times in clinically relevant sub-regions in healthy ACLs. Methods: Healthy males (n=20) and females (n=20) were assessed via 3T magnetic resonance imaging. T2 weighted structural imaging was performed to obtain ACL volume. T2 and T2* relaxation imaging were then performed. The ACL was sub-divided into proximal, middle and distal thirds where regional T2 and T2* relaxation times were calculated. A 1 between (sex) and 3 within (sub-region) RMANOVA compared T2 and T2* relaxation times. Results: For the T2 relaxation analysis, the middle sub-region was greater than the proximal sub-region, and males had greater distal sub-region relaxation times than females. T2* relaxation times were significant greater in the distal than proximal and middle sub-regions in males and females. Conclusion: This is the first report of in vivo T2 and T2* ACL relaxation times in healthy individuals. Relaxation times were generally less in proximal portions of the ligament suggesting a nonuniform ligamentous structure. Level of evidence: IV. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of Muscles, Ligaments & Tendons Journal (MLTJ) is the property of CIC Edizioni Internazionali s.r.l. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
    • Author Affiliations:
      1Department of Kinesiology & Gateway MRI Center, University of North Carolina-Greensboro, USA
      2Department of Sports Medicine, China Medical University Taiwan, China
      3Department of Educational Research Methodology University of North Carolina-Greensboro, USA
      4College of Health, University of Utah, USA
    • ISSN:
      2240-4554
    • Accession Number:
      130371563
  • Citations
    • ABNT:
      SCHMITZ, R. J. et al. Regional differences in anterior cruciate ligament imaging biomarkers: T2 and T2* values. Muscles, Ligaments & Tendons Journal (MLTJ), [s. l.], v. 8, n. 2, p. 238–245, 2018. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=130371563&custid=s8280428. Acesso em: 22 fev. 2020.
    • AMA:
      Schmitz RJ, Hsin-Min Wang, Kraft RA, et al. Regional differences in anterior cruciate ligament imaging biomarkers: T2 and T2* values. Muscles, Ligaments & Tendons Journal (MLTJ). 2018;8(2):238-245. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=130371563&custid=s8280428. Accessed February 22, 2020.
    • APA:
      Schmitz, R. J., Hsin-Min Wang, Kraft, R. A., Shultz, S. J., Ross, S. E., Henson, R. A., & Perrin, D. H. (2018). Regional differences in anterior cruciate ligament imaging biomarkers: T2 and T2* values. Muscles, Ligaments & Tendons Journal (MLTJ), 8(2), 238–245.
    • Chicago/Turabian: Author-Date:
      Schmitz, Randy J., Hsin-Min Wang, Robert A. Kraft, Sandra J. Shultz, Scott E. Ross, Robert A. Henson, and David H. Perrin. 2018. “Regional Differences in Anterior Cruciate Ligament Imaging Biomarkers: T2 and T2* Values.” Muscles, Ligaments & Tendons Journal (MLTJ) 8 (2): 238–45. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=130371563&custid=s8280428.
    • Harvard:
      Schmitz, R. J. et al. (2018) ‘Regional differences in anterior cruciate ligament imaging biomarkers: T2 and T2* values’, Muscles, Ligaments & Tendons Journal (MLTJ), 8(2), pp. 238–245. Available at: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=130371563&custid=s8280428 (Accessed: 22 February 2020).
    • Harvard: Australian:
      Schmitz, RJ, Hsin-Min Wang, Kraft, RA, Shultz, SJ, Ross, SE, Henson, RA & Perrin, DH 2018, ‘Regional differences in anterior cruciate ligament imaging biomarkers: T2 and T2* values’, Muscles, Ligaments & Tendons Journal (MLTJ), vol. 8, no. 2, pp. 238–245, viewed 22 February 2020, .
    • MLA:
      Schmitz, Randy J., et al. “Regional Differences in Anterior Cruciate Ligament Imaging Biomarkers: T2 and T2* Values.” Muscles, Ligaments & Tendons Journal (MLTJ), vol. 8, no. 2, Apr. 2018, pp. 238–245. EBSCOhost, search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=130371563&custid=s8280428.
    • Chicago/Turabian: Humanities:
      Schmitz, Randy J., Hsin-Min Wang, Robert A. Kraft, Sandra J. Shultz, Scott E. Ross, Robert A. Henson, and David H. Perrin. “Regional Differences in Anterior Cruciate Ligament Imaging Biomarkers: T2 and T2* Values.” Muscles, Ligaments & Tendons Journal (MLTJ) 8, no. 2 (April 2018): 238–45. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=130371563&custid=s8280428.
    • Vancouver/ICMJE:
      Schmitz RJ, Hsin-Min Wang, Kraft RA, Shultz SJ, Ross SE, Henson RA, et al. Regional differences in anterior cruciate ligament imaging biomarkers: T2 and T2* values. Muscles, Ligaments & Tendons Journal (MLTJ) [Internet]. 2018 Apr [cited 2020 Feb 22];8(2):238–45. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=130371563&custid=s8280428