A review on evaluation of technetium-99m labeled radiopharmaceuticals.

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  • معلومة اضافية
    • Author-Supplied Keywords:
      Amino acids
      Antibiotics
      Antibodies
      Labeling
      Peptides
      pH
      Tc
    • NAICS/Industry Codes:
      325410 Pharmaceutical and medicine manufacturing
      325411 Medicinal and Botanical Manufacturing
      414510 Pharmaceuticals and pharmacy supplies merchant wholesalers
      424210 Drugs and Druggists' Sundries Merchant Wholesalers
    • Abstract:
      In the past few years, substantial progress has been made in technetium chemistry, including the synthesis of a variety of Tc-radiopharmaceuticals. This synthesis can be made feasible by using suitable reducing agents, highly specific ligands, appropriate buffer, and specific pH etc., which results in high radiochemical purity, minimum labeling time, commercial expediency of Mo/Tc generator and high biological efficacy. Tc-radiopharmaceuticals have confirmed their worth in every span of life, especially in clinical and medical applications. Now Tc based pharmaceuticals are being used as diagnostic agents for a large number of infections caused by bacteria or any pathogens, tumors, cancers, ulcers etc. In this review, we discuss synthesis of a variety of Tc carrying biological molecules (antibiotics/antibodies/peptides/amino acids/macro and micro-organic molecules) along with their applications, to overview key innovations. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of Journal of Radioanalytical & Nuclear Chemistry is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
    • Author Affiliations:
      1Department of Bioinformatics and Biotechnology , Government College University , Faisalabad 38000 Pakistan
      2Department of Chemistry, Faculty of Science , The Islamia University of Bahawalpur , Bahawalpur 63100 Pakistan
      3Department of Radiation Biotechnology and Applied Radioisotope Science , Korea University of Science and Technology , Daejeon 305-350 Republic of Korea
    • ISSN:
      0236-5731
    • Accession Number:
      10.1007/s10967-016-5019-7
    • Accession Number:
      118416818
  • Citations
    • ABNT:
      AKBAR, M. et al. A review on evaluation of technetium-99m labeled radiopharmaceuticals. Journal of Radioanalytical & Nuclear Chemistry, [s. l.], v. 310, n. 2, p. 477–493, 2016. DOI 10.1007/s10967-016-5019-7. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=118416818&custid=s8280428. Acesso em: 28 jan. 2020.
    • AMA:
      Akbar M, Ahmad M, Shaheen A, Mushtaq S. A review on evaluation of technetium-99m labeled radiopharmaceuticals. Journal of Radioanalytical & Nuclear Chemistry. 2016;310(2):477-493. doi:10.1007/s10967-016-5019-7.
    • APA:
      Akbar, M., Ahmad, M., Shaheen, A., & Mushtaq, S. (2016). A review on evaluation of technetium-99m labeled radiopharmaceuticals. Journal of Radioanalytical & Nuclear Chemistry, 310(2), 477–493. https://doi.org/10.1007/s10967-016-5019-7
    • Chicago/Turabian: Author-Date:
      Akbar, Muhammad, Muhammad Ahmad, Aqeela Shaheen, and Sajid Mushtaq. 2016. “A Review on Evaluation of Technetium-99m Labeled Radiopharmaceuticals.” Journal of Radioanalytical & Nuclear Chemistry 310 (2): 477–93. doi:10.1007/s10967-016-5019-7.
    • Harvard:
      Akbar, M. et al. (2016) ‘A review on evaluation of technetium-99m labeled radiopharmaceuticals’, Journal of Radioanalytical & Nuclear Chemistry, 310(2), pp. 477–493. doi: 10.1007/s10967-016-5019-7.
    • Harvard: Australian:
      Akbar, M, Ahmad, M, Shaheen, A & Mushtaq, S 2016, ‘A review on evaluation of technetium-99m labeled radiopharmaceuticals’, Journal of Radioanalytical & Nuclear Chemistry, vol. 310, no. 2, pp. 477–493, viewed 28 January 2020, .
    • MLA:
      Akbar, Muhammad, et al. “A Review on Evaluation of Technetium-99m Labeled Radiopharmaceuticals.” Journal of Radioanalytical & Nuclear Chemistry, vol. 310, no. 2, Nov. 2016, pp. 477–493. EBSCOhost, doi:10.1007/s10967-016-5019-7.
    • Chicago/Turabian: Humanities:
      Akbar, Muhammad, Muhammad Ahmad, Aqeela Shaheen, and Sajid Mushtaq. “A Review on Evaluation of Technetium-99m Labeled Radiopharmaceuticals.” Journal of Radioanalytical & Nuclear Chemistry 310, no. 2 (November 2016): 477–93. doi:10.1007/s10967-016-5019-7.
    • Vancouver/ICMJE:
      Akbar M, Ahmad M, Shaheen A, Mushtaq S. A review on evaluation of technetium-99m labeled radiopharmaceuticals. Journal of Radioanalytical & Nuclear Chemistry [Internet]. 2016 Nov [cited 2020 Jan 28];310(2):477–93. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=118416818&custid=s8280428